Mavenclad (4 tablet pack) cladribine
Cladribine is used to treat relapsing forms of multiple sclerosis (MS). It is not a cure for MS but it is thought to help by preventing immune system cells (lymphocytes) from attacking the nerves in your brain and spinal cord. It may help to slow disease worsening and decrease flare-ups of symptoms.
How to use:
Read the Medication Guide provided by your pharmacist before you start taking cladribine and each time you get a refill. If you have any questions, ask your doctor or pharmacist. Take this medication by mouth with or without food as directed by your doctor. The dosage is based on your medical condition, weight, and response to treatment. You should usually only take this medication for 2 treatment weeks (with about a month separating each treatment week) each year for 2 years. After completing the 2-year treatment course, do not take cladribine during the next 2 years. Follow your doctor’s instructions carefully. Wash and dry your hands before handling this medication. Swallow the tablet(s) whole. Do not crush or chew the tablets. After taking the medication, wash your hands with soap and water. Take this medication at least 3 hours before or after taking other medications. If the tablet breaks, avoid inhaling the powder or dust, and avoid direct contact with the skin or eyes. If contact occurs, wash the affected skin well with soap and water or rinse your eyes with plain water. Consult your pharmacist for details. Since this drug can be absorbed through the skin and lungs and may harm an unborn baby, women who are pregnant or who may become pregnant should not handle this medication or breathe the dust from the tablets.
See also Warning section. Nausea, headache, back pain, or stomach/abdominal pain may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly. People using this medication may have serious side effects. However, your doctor has prescribed this drug because he or she has judged that the benefit to you is greater than the risk of side effects. Careful monitoring by your doctor may decrease your risk. Tell your doctor right away if you have any serious side effects, including: signs of liver problems (such as nausea/vomiting that doesn’t stop, loss of appetite, severe stomach/abdominal pain, yellowing eyes/skin, dark urine). This medication decreases bone marrow function, an effect that may lead to a low number of blood cells such as red cells, white cells, and platelets. This effect can cause anemia, decrease your body’s ability to fight an infection, or cause easy bruising/bleeding. Tell your doctor right away if you develop any of the following symptoms: unusual tiredness, pale skin, signs of infection (such as sore throat that doesn’t go away, fever, chills, painful rash/sores, frequent/painful urination), easy bruising/bleeding. This medication may increase your risk of getting a rare but very serious (possibly fatal) brain infection (progressive multifocal leukoencephalopathy-PML). Get medical help right away if you have any of these side effects: clumsiness, loss of coordination/balance, weakness, sudden change in your thinking (such as confusion, difficulty concentrating, memory loss), difficulty talking/walking, seizure, vision changes. Get medical help right away if you have any very serious side effects, including: shortness of breath, fast/irregular heartbeat, swelling of the ankles/feet. A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.